By Christopher R. Jacobs, Daniel J. Kelly (auth.), Paulo R. Fernandes, Paulo Jorge Bártolo (eds.)
ISBN-10: 9400712537
ISBN-13: 9789400712539
ISBN-10: 9400712545
ISBN-13: 9789400712546
This ebook offers a set of chapters describing the state-of-the-art on computational modelling and fabrication in tissue engineering.
Tissue Engineering is a multidisciplinary box regarding scientists from diversified fields. the advance of mathematical tools is sort of appropriate to appreciate mobile biology and human tissues in addition to version, layout and fabricate optimized and clever scaffolds.
The bankruptcy authors are the prestigious keynote audio system on the first Eccomas thematic convention on Tissue Engineering the place the emphasis used to be on mathematical and computational modeling for scaffold layout and fabrication. this actual quarter of tissue engineering, whose target is to acquire substitutes for tough tissues comparable to bone and cartilage, is transforming into in value.
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Extra resources for Advances on Modeling in Tissue Engineering
Example text
1: Homogenized permeability tensors obtained for the designs shown in figure 8. 3 (30%) is assured in all spatial directions. The resulting microstructure designs are shown in figures 9 to 11. The volume fraction constraint is also an active constraint in all these designs, which means 50% of volume fraction for all designs. These figures present the single cell and the corresponding generated periodical pattern for both solid and fluid domains. Table 2 shows the homogenized permeability tensors for the optimal designs.
Jeong, J Jakob Schwiedrzik, Anna G. R. J. V. 2011 35 36 Scott J. Hollister et al. interaction, however, occurs through a number of paths, from the local cell material interaction (both attachment and cell deformation) occurring at the micron scale, to the nutrient/waste diffusion and deformation of millions of cells at the hundreds of microns to millimeter scale, to the whole tissue/organ scaffold interaction at the tens of centimeter scale. In short, we need to understand cellmaterial attachment, cell-material deformation mechanics, and cell-material mass transport characteristics to engineer a scaffold that reproducibly ensures optimal tissue regeneration.
For this Nonlinear Elastic Scaffold Design 45 chapter, we will instead focus on base scaffold materials that exhibit nonlinear elastic behavior and how the introduction of porosity alters these base nonlinear elastic properties. An important starting question is whether we can estimate a priori how close a scaffold fabricated from a nonlinear biomaterial can match the nonlinear behavior of a given soft tissue. In this regard, bounds on effective anisotropic nonlinear elastic behavior would be extremely useful.
Advances on Modeling in Tissue Engineering by Christopher R. Jacobs, Daniel J. Kelly (auth.), Paulo R. Fernandes, Paulo Jorge Bártolo (eds.)
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