By R. T. Johnson (auth.), Professor R. T. Johnson, Professor G. Lyon (eds.)
ISBN-10: 9400912439
ISBN-13: 9789400912434
ISBN-10: 9401070512
ISBN-13: 9789401070515
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H. (1983/1984). Myelin-associated glycoprotein in development and disease. v. , 6, 285-303 34 DYSMYELINA nON IN TRANSGENIC MICE 20. Eng, L. F. (1980). The glial fibrillary acidic (GFA) protein. In Bradshaw, R. A. and Schneider, D. ) Proteins of the Nervous System. pp. 85-117. (New York: Raven Press) 21. Hogan, E. L. and Greenfield, S. (1982). Animal models of genetic disorders of myelin. In Morell, P. ) Myelin. , pp. 489-534. (New York: Plenum Press) 22. DePamphilis, M. L. and Wassarman, P. M. (1982).
J. Neurochem, 40, 47-54 15. Trapp, B. , Tennekoon, G. and Griffin, J. (1987). Spatial segregation of mRNA encoding myelin-specific proteins. Proc. Natl. A cad. Sci. USA, 84, 7773-7 16. Trapp, B. , Small, J. , Khoury, G. and Scangos, G. A. (1988). Dysmyelination in transgenic mice containing JC virus early region. Ann. , 23, 38-48 17. , Khoury, G. and Salzman, N. P. (1984). JC virus enhancer-promoter active in human brain cells. Science, 226, 1337-9 18. Lees, M. B. and Brostaff, S. W. (1984). Proteins of myelin.
In this case, however, the deletion does not cover the 5'LTR nor the 3' half of the provirus. We recently cloned and sequenced such a provirus. The deletion expanded over more than 4 kb from nucleotide 1030 in the p24 gene up to nucleotide 5332 in the middle of the gp51 gene, thus eliminating the spliced-in fragment at the end of the pol gene conserved in the trans-activation of transcription (tat) mRNA of trans-activating viruses (BL V, HTLV -I and II). Is the deleted provirus able to code for a functional tat-BLV protein?
Virus Infections and the Developing Nervous System by R. T. Johnson (auth.), Professor R. T. Johnson, Professor G. Lyon (eds.)
by Richard
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